What causes hypertension post bilateral nephrectomy?
History includes nephrotic syndrome
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With current immunosuppression, high blood pressure by almost 90% of kidney transplant recipients are. The main causes of this are the deterioration of renal function (secondary chronic graft nephropathy or less frequent recurrence of primary renal disease), use of calcineurin inhibitors as immunosuppressive agents, uncontrolled renin secretion by the kidneys shrunken the recipient, stenosing lesions of the transplant artery (or arteries upstream from the receiver), polycythemia and genetic predisposition to hypertension transplant donor. Even slight degree of increased blood pressure have a significant effect on recipient survival and graft survival, presumably by amplifying the vascular injury of the graft. In this regard, elevated systolic blood pressure and an abnormal profile of blood pressure circadian particular importance. In contrast to previous opinion, angiotensin converting enzyme inhibitors are indicated for the treatment, but given the causal role of sodium retention and vasoconstriction of the graft, diuretics and calcium antagonists remain pillars of antihypertensive treatment in renal transplant recipients
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